Inicio > Matemáticas y ciencia > Biologia, ciencias de la vida > Kurkumina hamowała endotelinę-1 w sercu szczurów leczonych lindanem
Kurkumina hamowała endotelinę-1 w sercu szczurów leczonych lindanem

Kurkumina hamowała endotelinę-1 w sercu szczurów leczonych lindanem

Amal Ibrahim

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Biologia, ciencias de la vida
ISBN:
9786209123900
58,82 €
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Sobre IBD

Lindan (gamma-heksachloroheksan) jest najbardziej toksycznym ze wszystkich izomerów heksachloroheksanu i ma silne właściwości owadobójcze. Jest stosowany do zwalczania owadów upraw polowych i szkodników w domach. Jedną z głównych dróg narażenia ludzi jest skażenie żywności, gdzie jego pozostałości znaleziono w wodzie, mleku, oleju spożywczym i rybach. Uważa się, że lindan oddziałuje na wątrobę, zakłócając jej zdolność utleniania i metabolizm glutationu. Pierwszym celem niniejszego badania było zbadanie histopatologicznego wpływu lindanu na serce oraz roli CK i ET-1 w toksyczności serca u samców szczurów. Drugim celem było sprawdzenie hipotezy, że kurkumina ma działanie kardioprotekcyjne i przeciwutleniające, chroniące przed tymi toksycznymi skutkami.

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