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Formulazione e sviluppo di microsfere di diclofenac e rabeprazolo

Formulazione e sviluppo di microsfere di diclofenac e rabeprazolo

Akanksha Garud / Anshita Gupta / Navneet Garud

69,60 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786208777548
69,60 €
IVA incluido
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Sobre IBD

Le microsfere sono vettori che sono stati frequentemente utilizzati per il rilascio prolungato di vari farmaci. Il rilascio di FANS nello stomaco provoca diverse implicazioni, una delle quali è l’erosione della mucosa gastrica e l’ulcerazione. Per prevenire questo fenomeno, alcuni inibitori della pompa protonica possono essere somministrati insieme al diclofenac. Il presente sistema è stato progettato in modo tale da somministrare entrambi i farmaci in un sistema che li rilascia a pH alcalino e ne impedisce la degradazione a pH acido, cioè nello stomaco, riducendo così al minimo i loro effetti collaterali e rendendolo anche un sistema a rilascio prolungato che aumenta la compliance del paziente.

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Otros libros del autor

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