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Formuła i rozwój mikrosfer diklofenaku i rabeprazolu

Formuła i rozwój mikrosfer diklofenaku i rabeprazolu

Akanksha Garud / Anshita Gupta / Navneet Garud

69,60 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786208777500
69,60 €
IVA incluido
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Sobre IBD

Mikrosfery są nośnikami często stosowanymi do przedłużonego uwalniania różnych leków. Uwalnianie NLPZ w żołądku powoduje szereg konsekwencji, z których jedną z głównych jest erozja błony śluzowej żołądka i owrzodzenie. Aby temu zapobiec, niektóre inhibitory pompy protonowej mogą być również podawane z diklofenakiem. Obecny system został zaprojektowany w taki sposób, aby dostarczać oba leki w systemie, który dostarcza lek w zasadowym pH i zapobiega jego degradacji w kwaśnym pH, tj. w żołądku, minimalizując w ten sposób ich skutki uboczne, a także czyniąc go systemem o przedłużonym uwalnianiu, który zwiększa przestrzeganie zaleceń przez pacjentów.

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