Inicio > Medicina > Otras ramas de la medicina > Farmacología > Farmacocinetica della moxifloxacina nella capra
Farmacocinetica della moxifloxacina nella capra

Farmacocinetica della moxifloxacina nella capra

Adil Mehraj Khan / GURMEET SINGH / Mudasir Sultana

64,89 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Farmacología
ISBN:
9786207978458
64,89 €
IVA incluido
Disponible

Selecciona una librería:

  • Librería Samer Atenea
  • Librería Aciertas (Toledo)
  • Kálamo Books
  • Librería Perelló (Valencia)
  • Librería Elías (Asturias)
  • Donde los libros
  • Librería Kolima (Madrid)
  • Librería Proteo (Málaga)

La farmacocinetica della moxifloxacina @ 5mg.kg-1.b.wt è stata studiata in capre sane e intossicate da bifentrin (n=4), dopo la sua somministrazione endovenosa. La MIC della moxifloxacina nel plasma è stata mantenuta fino a 8 ore nelle capre sane, mentre è stata mantenuta solo fino a 6 ore nelle capre intossicate da bifentrin. L’AUC è diminuita significativamente da 7,86±0,06g,ml-1h a 6,90±0,076g,ml-1h nelle capre intossicate da bifentrin. L’emivita di distribuzione (t½) e il volume di distribuzione allo stato stazionario Vd(ss) ¬osservati erano rispettivamente 0,08±0,0008 h e 2,43±0,01L.kg-1 nelle capre sane e 0,081±0,0006h e 2,32±0,03L.kg-1 nelle capre intossicate da bifentrin. La clearance corporea totale è aumentata da 636,06±4,68 ml.kg-1h-1 nelle capre sane a 725,4±7,92 ml.kg-1h-1 nelle capre intossicate. Tuttavia, nelle capre intossicate è stata osservata una diminuzione dell’emivita di eliminazione (t1/2) da 2,81±0,04h a 2,61±0,01h. Il regime di dosaggio della moxifloxacina calcolato negli animali sani è di 4,99 mg.kg-1 seguiti da 4,73 mg.kg-1 a intervalli di 12 ore, efficace contro gli isolati batterici con MIC ≤ 0,1µg.ml-1 . Tuttavia, nelle capre intossicate, è di 6,66 mg.kg-1 seguita da 6,33 mg.kg-1 a 12 ore di intervallo.

Artículos relacionados

  • Identification and Characterization of Antimicrobial Peptides with Therapeutic Potential
    Guangshun Wang
    Antimicrobial peptides are key defense molecules adopted by all life forms to prevent infection. They also have other beneficial effects such as boosting immune response, anticancer, and wound healing. The antiviral effects of antimicrobial peptides have laid the foundations for developing new agents to combat seasonal Flu, HIV-1, RSV, Zika, and Ebola. This eBook is constructed...
    Disponible

    67,96 €

  • Mind Maps of Clinical Research Basics
    Amrita Akhouri
    The concepts of Clinical Research have been depicted through mind maps in this book which makes the subject fundamentals very easy to understand and convenient to revise. The chapter on career in clinical research gives an insight into the main job roles currently known in this field along with the focus on how to build preparedness for job interviews. Hence, this book will be ...
    Disponible

    25,42 €

  • Marine Polysaccharides Volume 2
    Paola Laurienzo
    The field of marine polysaccharides is constantly evolving, due to progress in the discovery and production of new marine polysaccharides. Seaweed remains the most abundant source of polysaccharides, but recent advances in biotechnology have allowed the production of large quantities of polysaccharides from a variety of micro-algae, by controlling growth conditions and tailorin...
    Disponible

    75,84 €

  • Marine Polysaccharides Volume 3
    Paola Laurienzo
    The field of marine polysaccharides is constantly evolving, due to progress in the discovery and production of new marine polysaccharides. Seaweed remains the most abundant source of polysaccharides, but recent advances in biotechnology have allowed the production of large quantities of polysaccharides from a variety of micro-algae, by controlling growth conditions and tailorin...
    Disponible

    116,84 €

  • Herbs Used for Hair Growth
    Devi Raman / V. Varalakshmi
    Natural medicine has many benefits, from nourishing the scalp to stimulating hair follicles. Some popular herbs that aid hair growth include rosemary, ginseng, aloe vera, and fenugreek. Each plant has unique properties that help strengthen hair, prevent breakage, and promote growth, healthy growth. Of course, many herbs are popular for their beneficial effects in promoting hair...
    Disponible

    54,32 €

  • Novel Anti-proliferative Agents
    Valentina Onnis
    This Special Issue of Pharmaceuticals presented the recent findings on antiproliferative compounds and highlighted possible routes to discover new drugs used to treat cancer. In this Special Issue, different studies on kinase and methyltransferase-like proteins 3 inhibitors and compounds capable of altering the tumor microenvironment or acting at the mitotic stage of the cell c...

Otros libros del autor

  • Farmacocinética da Moxifloxacina em Caprinos
    Adil Mehraj Khan / GURMEET SINGH / Mudasir Sultana
    A farmacocinética da moxifloxacina @ 5mg.kg-1.b.wt foi estudada em cabras saudáveis e intoxicadas com bifentrina (n=4), após a sua administração IV. A CIM da moxifloxacina no plasma foi mantida até 8h em cabras saudáveis, enquanto que foi mantida apenas até 6h em cabras intoxicadas com bifentrina. A AUC diminuiu significativamente de 7,86±0,06g.ml-1h para 6,90±0,076g.ml-1h em...
    Disponible

    64,89 €

  • Pharmakokinetik von Moxifloxacin bei Ziegen
    Adil Mehraj Khan / GURMEET SINGH / Mudasir Sultana
    Die Pharmakokinetik von Moxifloxacin @ 5mg.kg-1.Körpergewicht wurde bei gesunden und Bifenthrin-intoxizierten Ziegen (n=4) nach intravenöser Verabreichung untersucht. Die MHK von Moxifloxacin im Plasma wurde bei gesunden Ziegen bis zu 8 Stunden aufrechterhalten, während sie bei Bifenthrin-intoxizierten Ziegen nur bis zu 6 Stunden aufrechterhalten wurde. Die AUC war bei Bifenthr...
    Disponible

    64,95 €

  • Pharmacocinétique de la moxifloxacine chez la chèvre
    Adil Mehraj Khan / GURMEET SINGH / Mudasir Sultana
    La pharmacocinétique de la moxifloxacine @ 5mg.kg-1.b.wt a été étudiée chez des chèvres saines et intoxiquées à la bifenthrine (n=4), après son administration IV. La CMI de la moxifloxacine dans le plasma a été maintenue jusqu’à 8 heures chez les chèvres saines alors qu’elle n’a été maintenue que jusqu’à 6 heures chez les chèvres intoxiquées par la bifenthrine. L’ASC a été sign...
    Disponible

    64,89 €

  • Pharmacokinetics of Moxifloxacin in Goats
    Adil Mehraj Khan / GURMEET SINGH / Mudasir Sultana
    Pharmacokinetics of moxifloxacin @ 5mg.kg-1.b.wt was studied in healthy and bifenthrin intoxicated goats (n=4), following its IV administration. The MIC of moxifloxacin in plasma was maintained up to 8h in healthy goats whereas it was maintained only up to 6h in bifenthrin-intoxicated goats. The AUC was significantly decreased from 7.86±0.06g.ml-1h to 6.90±0.076g.ml-1h in bif...
    Disponible

    63,86 €