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Confronto tra metodi di estrazione per un farmaco antitumorale, la vinblastina

Confronto tra metodi di estrazione per un farmaco antitumorale, la vinblastina

Shagufta Naz / Sumera Javad / Sumera Sarwar

67,97 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Botánica y ciencias de las plantas
ISBN:
9786209576959
67,97 €
IVA incluido
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Nel presente studio è stato effettuato un confronto tra diversi metodi di estrazione del farmaco antitumorale Vinblastina dal Catharanthus roseus. L’estrazione è stata effettuata utilizzando due metodi diversi, ovvero l’estrazione assistita da microonde (MAE) e l’estrazione Soxhlet utilizzando etanolo e alcune gocce di HCl concentrato come solvente di estrazione. La stima della vinblastina è stata effettuata utilizzando la cromatografia liquida ad alta prestazione (HPLC) con acetonitrile come fase mobile. L’estrazione assistita da microonde si è dimostrata un approccio migliore per l’estrazione rapida ed efficiente della vinblastina dal materiale vegetale. È stato riscontrato che l’estrazione assistita da microonde ha fornito la quantità massima di estratto di Catharanthus roseus, pari a 0,43 g, utilizzando un tempo di estrazione inferiore (30 secondi) e una quantità molto ridotta di solvente (10 mL/g) rispetto all’estrazione Soxhlet (23,01 g in 10 ore).

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