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Bases moleculares da oncologia da cabeça e do pescoço

Bases moleculares da oncologia da cabeça e do pescoço

Dhinakaran Paranchodi / Ramya Selvam / Shaleen Chandra

73,52 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786209897269
73,52 €
IVA incluido
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Os cânceres de cabeça e pescoço ocupam uma interseção singular entre biologia, medicina e experiência humana. Eles surgem em regiões essenciais para a respiração, fala, deglutição e percepção sensorial, o que significa que seu impacto é frequentemente sentido precocemente. Por trás de cada tumor visível, existe um cenário molecular complexo e em grande parte invisível - alterações genéticas, alterações epigenéticas, vias de sinalização anormais e mudanças microambientais que impulsionam a transformação de células normais em malignas.Este livro começa nesse espaço molecular onde a oncogênese se origina. Nas últimas décadas, os avanços científicos transformaram significativamente nossa compreensão de como os cânceres de cabeça e pescoço se desenvolvem e progridem. Antes vistos principalmente sob perspectivas anatômicas e histopatológicas, esses cânceres agora são reconhecidos como doenças moldadas por mecanismos moleculares identificáveis. Descobertas como o papel do papilomavírus humano de alto risco em certos cânceres orofaríngeos, insights obtidos por meio do sequenciamento de alto rendimento sobre os padrões mutacionais e uma compreensão mais profunda das interações tumor-imune remodelaram a narrativa da oncogênese.

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