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Transdermal Patch of Lamivudine and Stavudine-Loaded Ethosomes

Transdermal Patch of Lamivudine and Stavudine-Loaded Ethosomes

Alok Pail Jain / Ravikant Gupta / Shailesh Gupta

49,51 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2020
Materia
Farmacología
ISBN:
9786200788641
49,51 €
IVA incluido
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Sobre IBD

TDDS are the ideal delivery system for drug that undergo hepatic first pass metabolism. Lamivudine and Stavudune drug was successfully designed and developed by trial and error method. Formulations were prepared by employing combination of HPMCK15M, PVPK30, and EC in various ratios. From the evaluation results it was conclude that TF5 show highest release at 12 hrs. with suitable polymer ratio and penetration enhancer and it was observed that Higuchi kinetics model most suitable kinetic model for drug release from all patches.

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