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Systems Biological Approaches in Infectious Diseases

Systems Biological Approaches in Infectious Diseases

 

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Editorial:
Springer Nature B.V.
Año de edición:
2006
Materia
Biología molecular
ISBN:
9783764375669

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  • Librería Samer Atenea
  • Librería Aciertas (Toledo)
  • Kálamo Books
  • Librería Perelló (Valencia)
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  • Librería Kolima (Madrid)
  • Librería Proteo (Málaga)

Systems biology and its impact on anti-infective drug development.- Applications of transcriptional profiling in antibiotics discovery and development.- Chemical genetics: An evolving toolbox for target identification and lead optimization.- Proteomic profiling of cellular stresses in Bacillus subtilis reveals cellular networks and assists in elucidating antibiotic mechanisms of action.- Elucidating the mode-of-action of compounds from metabolite profiling studies.- A subsystems-based approach to the identification of drug targets in bacterial pathogens.- Metabolic control analysis to identify optimal drug targets.- The protein network as a tool for finding novel drug targets.- Toxicogenomics applied to predictive and exploratory toxicology for the safety assessment of new chemical entities: a long road with deep potholes.- The application of the theory of biological robustness to complex host-pathogen systems .- Toward whole cell modeling and simulation: comprehensive functional genomics through the constraint-based approach.- Genomics of host-pathogen interactions

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