Inicio > Matemáticas y ciencia > Química > Sensor fluorescente OFF-ON altamente seletivo para D-3-HB em solução aquosa
Sensor fluorescente OFF-ON altamente seletivo para D-3-HB em solução aquosa

Sensor fluorescente OFF-ON altamente seletivo para D-3-HB em solução aquosa

Qingming Wang

35,37 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Química
ISBN:
9786202328258
35,37 €
IVA incluido
Disponible

Selecciona una librería:

  • Librería Samer Atenea
  • Librería Aciertas (Toledo)
  • Kálamo Books
  • Librería Perelló (Valencia)
  • Librería Elías (Asturias)
  • Donde los libros
  • Librería Kolima (Madrid)
  • Librería Proteo (Málaga)
Sobre IBD

A cetoacidose diabética (CAD) é a emergência hiperglicémica mais comum em pacientes com diabetes e é causada pelo excesso de cetonas. Entre o total de corpos cetónicos, o ácido D-3-hidroxibutírico (D-3-HB) é o principal, representando quase 78%. Portanto, a deteção do D-3-HB sérico tem sido um marcador de rotina para o diagnóstico da cetoacidose diabética. A deteção por fluorescência é o método mais eficiente, simples de operar, de baixo custo, com monitorização em tempo real e alta sensibilidade. Aqui, duas novas sondas, 4-(2-hidroxibencilen)tiosemicarbazida (1) e 4-(1H-imidazo[4,5-f][1,10]-fenantrolin-2-il)fenol (2), foram sintetizadas e mostraram uma resposta fluorescente OFF-ON peculiar ao D-3-HB em solução aquosa. As sondas 1 e 2 exibiram uma resposta seletiva e sensível ao D-3-HB em relação a outros iões metálicos comuns, aniões e aminoácidos. Além disso, o mecanismo foi confirmado por 1H-NMR e ESI-MS. Além disso, esta sonda 1 foi aplicada com sucesso em bioimagem, demonstrando o seu valor para aplicações práticas em sistemas biológicos.

Artículos relacionados

  • Suzuki-Miyaura Cross-Coupling Reaction and Potential Applications
    Suzuki–Miyaura cross-coupling remains a powerful tool in organic synthesis for C–C bond formation and has various industrial applications, for example, the synthesis of pharmaceuticals and materials. Intensive research efforts are being made into finding ways of improving and expanding the scope of this process, and the development of more efficient catalytic systems for this e...
    Disponible

    67,89 €

  • Catalysis for Low Temperature Fuel Cells
    Today, the development of active and stable catalysts still represents a challenge to overcome in the research field of low temperature fuel cells. Operation at low temperatures demands the utilization of highly active catalysts to reduce the activation energy of the electrochemical reactions involved at the electrodes, and thus obtain practical performances and high efficienci...
    Disponible

    59,74 €

  • Trends in Microextraction Techniques for Sample Preparation
    Micro-extraction techniques in sample preparation are gaining interest among analytical chemists as they comply with green analytical chemistry demands and ensure environmental protection and public safety. Savings in cost and time are considered as valuable benefits by using novel micro-extraction approaches in sample handling. Selectivity, sensitivity and lower detection limi...
    Disponible

    59,87 €

  • Advances and Applications of Nano-antimicrobial Treatments
    Nowadays, great concerns are associated with the resistance demonstrated by many microorganisms towards the conventional antibiotic therapies. The failure of traditional antimicrobials, and the increasing healthcare costs, have encouraged scientific research and the development of novel antimicrobial agents. Particularly, there is a great deal of interest in nanotechnologies an...
    Disponible

    51,68 €

  • Handbook of Research on Uncovering New Methods for Ecosystem Management through Bioremediation
    Kajal Srivastava / Shivom Singh
    Maintaining and preserving the environment is a crucial consideration in an era where climate change and rising sea levels are common knowledge. It is important for researchers and developers alike to explore potential solutions for a steadily warming world. The Handbook of Research on Uncovering New Methods for Ecosystem Management through Bioremediation focuses on the agricul...
  • Structural Design and Properties of Coordination Polymers
    The assembly of organic ligands and metal centres yields coordination polymers, many of which find applications in conductivity, catalysis, magnetism, gas sorption, biological sensing and luminescence. The structure and topology of coordination polymers may be manipulated by changing the reaction conditions, leading to a large variety of structurally and topologically unique pr...
    Disponible

    43,77 €

Otros libros del autor

  • Wysoce selektywny czujnik fluorescencyjny typu OFF-ON do wykrywania D-3-HB w roztworach wodnych
    Qingming Wang
    Kwasica ketonowa cukrzycowa (DKA) jest najczęstszym stanem hiperglikemicznym u pacjentów z cukrzycą, spowodowanym zbyt wysokim poziomem ketonów. Wśród wszystkich ciał ketonowych głównym składnikiem jest kwas D-3-hydroksymaślanowy (D-3-HB), stanowiący prawie 78%. Dlatego wykrywanie D-3-HB w surowicy jest rutynowym markerem diagnostycznym kwasicy ketonowej cukrzycowej. Najskutecz...
    Disponible

    35,37 €

  • Sensore fluorescente OFF-ON altamente selettivo per D-3-HB in soluzione acquosa
    Qingming Wang
    La chetoacidosi diabetica (DKA) è l’emergenza iperglicemica più comune nei pazienti con diabete ed è causata da un eccesso di chetoni. Tra i corpi chetonici totali, l’acido D-3-idrossibutirrico (D-3-HB) è il principale, con quasi il 78%. Pertanto, il rilevamento del D-3-HB sierico è stato un marker di routine per la diagnosi della chetoacidosi diabetica. Il rilevamento fluoresc...
    Disponible

    35,37 €

  • Capteur fluorescent OFF-ON hautement sélectif pour le D-3-HB en solution aqueuse
    Qingming Wang
    L’acidocétose diabétique (ACD) est l’urgence hyperglycémique la plus courante chez les patients diabétiques, et elle est causée par un excès de cétones. Parmi l’ensemble des corps cétoniques, l’acide D-3-hydroxybutyrique (D-3-HB) est le principal, représentant près de 78 %. La détection du D-3-HB sérique est donc un marqueur de routine pour le diagnostic de l’acidocétose diabét...
    Disponible

    35,37 €

  • Hochselektiver OFF-ON-Fluoreszenzsensor für D-3-HB in wässrigen Lösungen
    Qingming Wang
    Die diabetische Ketoazidose (DKA) ist die häufigste hyperglykämische Notfallsituation bei Patienten mit Diabetes und wird durch einen zu hohen Ketonspiegel verursacht. Unter den gesamten Ketonkörpern macht D-3-Hydroxybuttersäure (D-3-HB) mit fast 78 % den größten Anteil aus. Daher ist der Nachweis von D-3-HB im Serum ein Routinemarker für die Diagnose einer diabetischen Ketoazi...
    Disponible

    35,37 €