Propriétés angiogéniques

Propriétés angiogéniques

Rekha Khandia

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Biologia, ciencias de la vida
ISBN:
9786208320737
66,23 €
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L’Inde a une longue tradition d’utilisation de médicaments à base de plantes. Les médicaments sont utilisés traditionnellement par différents groupes ethniques. Ces connaissances sont transmises d’une génération à l’autre. Ces médicaments sont considérés comme des ethnomédicaments. Ces médicaments ethniques sont utilisés sur la base de connaissances précédemment acquises, sans connaître leur composant chimique exact responsable de l’action. La présente étude comprend l’analyse phytochimique de 17 ethnomédicaments, couramment utilisés en Inde pour traiter plusieurs affections. Les capacités de modulation de l’angiogenèse de 4 ethnomédecines sélectionnées, Butea monosperma, Dioscorea hispida, Mesua ferrea et Myristica fragrans, ont également été évaluées. Le Butea monosperma s’est avéré avoir un effet angiogénique positif, alors que les trois autres ont eu un impact négatif sur l’angiogenèse dans le modèle de la membrane chorioallanotique (CAM) des œufs de poule embryonnés. Sur la base de l’analyse phytochimique, des modulateurs angiogéniques potentiels peuvent être sélectionnés et envisagés dans des modèles in vivo plus avancés.

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