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Prognóstico da permeação transdérmica in-vitro utilizando modelação in silico

Prognóstico da permeação transdérmica in-vitro utilizando modelação in silico

Bharti Sapra / Neha Goyal / Om Silakari

45,22 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Farmacología
ISBN:
9786208041526
45,22 €
IVA incluido
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Sobre IBD

A permeação cutânea das moléculas é um fenómeno multifatorial que depende de diversos tipos de interações físicas, químicas e biológicas. Os estudos de permeação cutânea in vitro são frequentemente realizados para o rastreio de moléculas e de sistemas de transporte de fármacos com o objetivo de otimizar a administração dérmica ou transdérmica. Os modelos matemáticos ajudam muitas vezes diretamente, fornecendo informações sobre a taxa de penetração do fármaco através da pele e, por conseguinte, sobre a concentração dérmica ou sistémica dos fármacos. Também são úteis na análise de dados experimentais, reduzindo o número de experiências e traduzindo o contexto in vitro.

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