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Opracowanie folii o kontrolowanym uwalnianiu do leczenia nadciśnienia tętniczego

Opracowanie folii o kontrolowanym uwalnianiu do leczenia nadciśnienia tętniczego

Ajit S Kulkarni / Nagesh H Aloorkar / SHIVPRASAD MAJUMDAR

74,69 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Farmacología
ISBN:
9786209905964
74,69 €
IVA incluido
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Sobre IBD

Nadciśnienie tętnicze stanowi poważne wyzwanie dla zdrowia publicznego na całym świecie ze względu na wysoką częstość występowania i związane z tym zwiększone ryzyko chorób. Celem niniejszego badania było opracowanie folii o kontrolowanym uwalnianiu chlorowodorku propranololu. Ze względu na skuteczność i powszechne stosowanie chlorowodorku propranololu jako leku z wyboru w leczeniu nadciśnienia tętniczego i zastoinowej niewydolności serca, w ramach badania postanowiono opracować doustną postać dawkowania o kontrolowanym uwalnianiu. Folia o kontrolowanym uwalnianiu chlorowodorku propranololu została przygotowana przy użyciu polimeru opóźniającego uwalnianie. Celem tej pracy było zaprojektowanie folii o kontrolowanym uwalnianiu przy użyciu metody odlewania z użyciem rozpuszczalnika, zbadanie stabilności preparatu oraz zbadanie parametrów polimeru przed formulacją. Na podstawie wyników badania można stwierdzić, że opracowana folia może stanowić przełom w dostarczaniu leków w sposób kontrolowany.

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