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Odporność antybakteryjna, co to jest?

Odporność antybakteryjna, co to jest?

Hisham Abdallah A. Yosef / Iman Hamed Imam Ismael / Nesrin Mahmoud Morsy Mohamed

72,27 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Química
ISBN:
9786209813672
72,27 €
IVA incluido
Disponible

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Sobre IBD

Stwierdzono, że kilka szczepów bakterii jest opornych na wiele antybiotyków. Bakterie te znane są jako bakterie wielolekooporne (MDR). Są one również nazywane superbakteriami. Do głównych superbakterii należą MDR Pseudomonas aeruginosa, MDR Escherichia coli, Enterococcus oporny na wankomycynę, Staphylococcus aureus oporny na metycylinę i Enterobacteriaceae oporne na karbapenemy. Bakterie MDR wykazują cztery główne mechanizmy oporności na antybiotyki. Mechanizmy te obejmują inaktywację lub modyfikację leku, zmianę celu lub miejsca wiązania, zmianę szlaku metabolicznego i zmniejszenie akumulacji leku. Ewolucja oporności na środki przeciwdrobnoustrojowe stale rośnie, a w 2019 r. około 1,27 miliona ludzi na całym świecie zmarło z powodu bakterii MDR. W związku z tym istnieje pilna potrzeba podjęcia większych wysiłków w celu znalezienia najlepszych możliwych strategii leczenia tych superbakterii. Obejmuje to opracowanie nowych antybiotyków o nowatorskich sposobach działania, takich jak antybiotyki wielokierunkowe, kombinacje antybiotyków i adiuwanty antybiotykowe, które mogą działać przeciwko tym wielolekoopornym szczepom.

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