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Nowoczesne systemy dostarczania leków

Nowoczesne systemy dostarczania leków

ELAVARASI E / JAYAKUMAR JAYADURKA / YUVARAJ AR

67,42 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786209486685
67,42 €
IVA incluido
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Sobre IBD

Nowe systemy dostarczania leków (NDDS) zrewolucjonizowały dziedzinę farmacji, zapewniając kontrolowane, ukierunkowane i zorientowane na pacjenta rozwiązania terapeutyczne. Konwencjonalne formulacje leków często napotykają ograniczenia, takie jak słaba biodostępność, szybki metabolizm, krótki okres półtrwania i toksyczność poza celem, co może zagrażać skuteczności terapeutycznej. NDDS obejmują zróżnicowany zakres technologii, w tym doustne systemy kontrolowanego uwalniania, plastry transdermalne, inhalatory płucne i donosowe, systemy iniekcyjne i wszczepialne, nośniki polimerowe i lipidowe, ukierunkowane nanocząsteczki oraz zaawansowane platformy reagujące na bodźce. Systemy te zwiększają stabilność leku, optymalizują farmakokinetykę i umożliwiają dostarczanie leku w określonym miejscu, zmniejszając tym samym ogólnoustrojowe skutki uboczne i poprawiając przestrzeganie zaleceń przez pacjentów. Ostatnie postępy w dziedzinie nanotechnologii, druku 3D, polimerów reagujących na bodźce i pęcherzyków/ekosomów zewnątrzkomórkowych dodatkowo zwiększyły potencjał terapeutyczny NDDS, umożliwiając precyzyjną terapię złożonych schorzeń, takich jak nowotwory, zaburzenia neurologiczne, choroby metaboliczne i przewlekłe stany zapalne.

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