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Neuronale Grundlagen der kognitiven Kontrolle über die Bewegungshemmung

Neuronale Grundlagen der kognitiven Kontrolle über die Bewegungshemmung

Kitty Zhe Xu

55,34 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Psicología
ISBN:
9786207680382
55,34 €
IVA incluido
Disponible

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Eine entscheidende Funktion der exekutiven Kontrolle ist die Fähigkeit, einen Handlungsplan flexibel zu unterdrücken oder zu ändern, wenn er kontextabhängig unangemessen ist. Mit Hilfe der menschlichen fMRT und einer kontextabhängigen Stoppsignalaufgabe (SST) fanden wir eine funktionelle Doppeldissoziation zwischen dem rechten ventrolateralen präfrontalen Kortex (rVLPFC) und dem bi-lateralen frontalen Augenfeld (FEF). Die Aktivierung des rVLPFC war mit der Erkennung und Kodierung der Bedeutung von Stoppsignalen und der Reaktionshemmung verbunden, während die FEF-Aktivität die motorische Leistung unabhängig von der Reiz-Reaktions-Zuordnung oder dem Kontext widerspiegelte. Außerdem waren die Bedeutung von Stoppsignalen und die Reaktionshemmung in separaten Regionen des rVLPFC repräsentiert. Diese Ergebnisse wurden durch elektrophysiologische Ableitungen im rVLPFC und im FEF eines Affen weiter bestätigt. Die Ergebnisse deuten darauf hin, dass die Hemmung eines geplanten Verhaltens nicht, wie bisher angenommen, von einem einzigen Gehirnsystem gesteuert wird, sondern von zwei neuronal unterschiedlichen Prozessen abhängt.

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