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Neurodegeneração do ferro

Neurodegeneração do ferro

Mateen A. Khan

109,81 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Biologia, ciencias de la vida
ISBN:
9786200537577
109,81 €
IVA incluido
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Sobre IBD

A investigação sobre a neurodegeneração do ferro tem crescido imenso nas últimas décadas e este progresso tem sido documentado em numerosos artigos. No entanto, poucas publicações se centram especificamente na sobrecarga de ferro no cérebro e na sobreexpressão da proteína precursora amiloide da doença de Alzheimer através das vias reguladoras do elemento responsivo ao ferro (IRE), apesar das muitas compilações que abrangem tópicos relacionados com o metabolismo do ferro e a doença de Alzheimer. Decifrar os mecanismos complexos da agregação amiloide e das vias de sinalização IRE é essencial para compreender os mistérios da progressão da doença de Alzheimer.Este livro, Iron Neurodegeneration, explica em pormenor como o metabolismo do ferro é regulado e como afecta o desenvolvimento de doenças neurodegenerativas. O objetivo principal é explorar a forma como os agregados amilóides se agregam através da tradução do ARNm do IRE e identificar potenciais alvos terapêuticos para doenças neurodegenerativas. Este livro destina-se a um público alargado: os profissionais especializados apreciarão as descrições e discussões aprofundadas, enquanto que os estudantes, investigadores e cientistas novos na matéria beneficiarão da introdução abrangente que fornece uma base intelectual sólida.

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