Inicio > Matemáticas y ciencia > Biologia, ciencias de la vida > Molecular identification of the CTX-M resistance gene in bacteria
Molecular identification of the CTX-M resistance gene in bacteria

Molecular identification of the CTX-M resistance gene in bacteria

Márcia Brazão / Rafael Nascimento de Assis

48,30 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Biologia, ciencias de la vida
ISBN:
9786207849734
48,30 €
IVA incluido
Disponible

Selecciona una librería:

  • Librería Samer Atenea
  • Librería Aciertas (Toledo)
  • Kálamo Books
  • Librería Perelló (Valencia)
  • Librería Elías (Asturias)
  • Donde los libros
  • Librería Kolima (Madrid)
  • Librería Proteo (Málaga)
Sobre IBD

The CTX-M resistance gene produces Extended Spectrum Beta-lactamase (ESBL) enzymes that are capable of inhibiting the action of broad-spectrum beta-lactam antimicrobials by irreversibly hydroxylating the amide bond of the beta-lactam ring of these antimicrobials. In general, the gene that codes for ESBLs is located on plasmids, and these enzymes are characterised by their ability to inactivate beta-lactam antimicrobials such as penicillins, cephalosporins and monobactams, with the exception of carbapenems. Its hydrolytic action towards antimicrobials can be interrupted with the use of beta-lactamase inhibitors such as clavulanic acid, sulbactam and tazobactam. The CTX-M gene originated from the mobilisation of beta-lactam resistance genes present in the chromosomes of Kluyvera spp. bacteria, which from point mutations derived into different subtypes of the gene, in response to the selective pressure intensified by the widespread indiscriminate use of beta-lactam antimicrobials.

Artículos relacionados

  • Viral Replication Complexes
    Viruses are obligate intracellular parasites that need to co-opt a living cell’s machinery for replication. At the heart of the viral replication machinery are the nucleic acid polymerases, which are responsible for efficiently copying the viral genome. This process must often be coordinated with other viral processes, including protein translation and viral packaging. The poly...
  • Advances in Flavivirus Research
    The flaviviruses are composed almost entirely of arthropod-borne viruses, a subset of which are responsible for millions of cases of human disease each year. Among these viruses are dengue virus—a scourge throughout the tropical regions of Asia and the Americas; yellow fever virus—the “original” hemorrhagic fever virus; and the recently emerged Zika virus. While the flaviviruse...
    Disponible

    51,85 €

  • Brain Asymmetry of Structure and/or Function
    Lesley J. Rogers / Lesley JRogers
    This edited book brings together research reports on the asymmetry of brain function in various species, including humans, dogs, birds, lizards and bees. As shown in a wide range of species, and, as we now know, not solely in humans, the left and right sides of the brain process information in different ways and control different responses or patterns of behaviour. Since this d...
    Disponible

    51,71 €

  • Fungal Pigments
    With the impact of globalization in research trends, the search for healthier life styles, the increasing public demand for natural, organic, and ‘clean labelled’ products, as well as the growing global market for natural colorants in economically fast-growing countries all over the world, filamentous fungi started to be investigated as readily available sources of chemically d...
    Disponible

    43,80 €

  • The Epithelialto- Mesenchymal Transition ( EMT ) in Cancer
    Joëlle Roche
    The epithelial-to-mesenchymal transition (EMT) is a highly dynamic process with multiple transitional states, by which epithelial cells can convert into a mesenchymal phenotype. This process involves loss of cellular adhesion and cellular polarity, and an improvement in migratory and invasive properties. It occurs during normal embryonic development, tissue regeneration, organ ...
    Disponible

    67,86 €

  • The Biology and Treatment of Myeloid Leukaemias
    There has been an observed decrease in the global mortality from cancer, mostly atributable to improved, particularly early, detection and prevention. For many carcinomas and leukaemias in adults, once the disease has reached a certain stage there are no therapies that are able to erradicate the cancer cells and cure patients. There has been progress in the treatment of acute m...
    Disponible

    51,85 €

Otros libros del autor

  • Molekulare Identifizierung des CTX-M-Resistenzgens in Bakterien
    Márcia Brazão / Rafael Nascimento de Assis
    Das CTX-M-Resistenzgen produziert Extended Spectrum Beta-Lactamase (ESBL)-Enzyme, die in der Lage sind, die Wirkung von Breitspektrum-Beta-Lactam-Antimikrobiotika durch irreversible Hydroxylierung der Amidbindung des Beta-Lactam-Rings dieser Antimikrobiotika zu hemmen. Im Allgemeinen befindet sich das Gen, das für ESBLs kodiert, auf Plasmiden, und diese Enzyme zeichnen sich dur...
    Disponible

    48,30 €

  • Identification moléculaire du gène de résistance CTX-M chez les bactéries
    Márcia Brazão / Rafael Nascimento de Assis
    Le gène de résistance CTX-M produit des enzymes bêta-lactamase à spectre étendu (BLSE) capables d’inhiber l’action des antimicrobiens bêta-lactame à large spectre en hydroxylant de manière irréversible la liaison amide de l’anneau bêta-lactame de ces antimicrobiens. En général, le gène qui code pour les BLSE est situé sur des plasmides et ces enzymes se caractérisent par leur c...
    Disponible

    48,30 €

  • Identificazione molecolare del gene di resistenza CTX-M nei batteri
    Márcia Brazão / Rafael Nascimento de Assis
    Il gene della resistenza CTX-M produce enzimi beta-lattamici a spettro esteso (ESBL) che sono in grado di inibire l’azione degli antimicrobici beta-lattamici ad ampio spettro idrossilando irreversibilmente il legame ammidico dell’anello beta-lattamico di questi antimicrobici. In generale, il gene che codifica per le ESBL è localizzato su plasmidi e questi enzimi sono caratteriz...
    Disponible

    48,30 €