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Micele polimerowe dla systemu dostarczania leków do oczu

Micele polimerowe dla systemu dostarczania leków do oczu

Manish Kumar / Sumaya Hussain

65,43 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786200771810
65,43 €
IVA incluido
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Polimerowe nanomicele stały się obiecującą platformą do dostarczania leków do oczu, oferując lepszą penetrację rogówki, przedłużoną retencję i zwiększoną biodostępność środków terapeutycznych. Te nanonośniki, składające się z amfifilowych kopolimerów, mogą rozpuszczać hydrofobowe leki, chronić je przed degradacją i ułatwiać ukierunkowane dostarczanie do oka. Niewielkie rozmiary i elastyczna struktura polimerowych nanomiceli umożliwiają im pokonywanie barier ocznych, w tym rogówki, spojówki i twardówki, oraz kontrolowane uwalnianie kapsułkowanego leku. Podejście to wykazało potencjał w leczeniu różnych chorób oczu, takich jak jaskra, zwyrodnienie plamki żółtej związane z wiekiem i zespół suchego oka, zapewniając trwałe i zlokalizowane dostarczanie leków, zmniejszając ogólnoustrojowe skutki uboczne i poprawiając przestrzeganie zaleceń przez pacjentów.

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