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Metoda HPTLC

Metoda HPTLC

Rajeshree Makwana

61,82 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786208725778
61,82 €
IVA incluido
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Sobre IBD

Opracowano i zwalidowano metodę HPTLC wskazującą na stabilność do oznaczania finerenonu w postaci sypkiej i w postaci tabletek. Metoda HPTLC została opracowana i zwalidowana zgodnie z wytycznymi ICH dotyczącymi oznaczania finerenonu w postaci sypkiej i w postaci tabletek. Opracowana metoda okazała się liniowa, dokładna, precyzyjna i odporna zgodnie z kryteriami akceptacji. Przeprowadzono badanie wymuszonej degradacji leku. Produkty degradacji zostały dobrze rozdzielone proponowaną metodą HPTLC. Leki są podatne na degradację w warunkach kwaśnych, zasadowych, utleniających, fotolitycznych i termicznych. Stwierdzono, że opracowana metoda może być stosowana do oznaczania finerenonu luzem i w postaci tabletek do rutynowej analizy.

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