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L’impact d’un comportement guidé par les sens sur le traitement neuronal à long terme

L’impact d’un comportement guidé par les sens sur le traitement neuronal à long terme

Vida Skreb

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Biologia, ciencias de la vida
ISBN:
9786208548865
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Grâce à l’imagerie à deux photons, nous avons étudié les changements de neuroplasticité dans la population neuronale du cortex somatosensoriel de la souris, correspondant aux moustaches (cortex à tonneaux). L’imagerie a été réalisée quotidiennement pendant des mois d’apprentissage d’une tâche complexe (tâche de choix forcé de deux alternatives). Nous avons constaté une augmentation de l’activité neuronale en réponse au même stimulus sensoriel en corrélation avec l’apprentissage. En outre, nous avons constaté des différences dans le traitement en ligne au niveau du cortex sensoriel primaire, selon que la souris était engagée sur le plan comportemental dans la tâche ou qu’elle ne montrait aucune réponse comportementale. Nous avons également comparé l’entraînement de rats et de souris à la même tâche complexe et constaté que les deux espèces apprenaient à des rythmes comparables.

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