Lesioni renali indotte da farmaci

Lesioni renali indotte da farmaci

Lalit Mohan Nainwal / Poonam Arora

92,12 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Empresa y gestión
ISBN:
9786202362221
92,12 €
IVA incluido
Disponible

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I reni, fondamentali per filtrare le scorie dell’organismo, sono altamente vulnerabili alla nefrotossicità indotta da farmaci, una delle principali cause di danno renale acuto (AKI) nei pazienti ospedalizzati, con una percentuale di casi fino al 60% legata a farmaci come antibiotici, chemioterapici e analgesici. Questo libro affronta l’urgente necessità di bilanciare l’innovazione farmacologica con la protezione dei reni. I recenti progressi hanno approfondito la comprensione della nefrotossicità, rivelando complessi meccanismi molecolari, genetici e guidati da biomarcatori, mentre i regimi multifarmacologici e l’invecchiamento della popolazione aggiungono ulteriore complessità. Pensato per medici, ricercatori e tirocinanti, il testo copre l’epidemiologia, la fisiopatologia, le classi di farmaci ad alto rischio, gli strumenti diagnostici (compresi i biomarcatori come la KIM-1 e la cistatina C) e le strategie di prevenzione, illustrate da casi di studio e dal quadro delle '6R della nefrotossicità'. Il libro, collaborativo e interdisciplinare, pone l’accento sulla gestione dei farmaci, sul monitoraggio vigile e sull’educazione dei pazienti. Il libro esplora anche le direzioni future, come la previsione del rischio genomico, la farmacovigilanza guidata dall’intelligenza artificiale e l’equità delle cure renali, con l’obiettivo di ispirare l’impegno per una prescrizione sicura e una stewardship renale.

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