Lavandula stoechas

Lavandula stoechas

Rim Ben Mansour / Sana BAHRI

66,73 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Biologia, ciencias de la vida
ISBN:
9786209435256
66,73 €
IVA incluido
Disponible

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Die idiopathische Lungenfibrose ist eine chronische und progressive Krankheit, die durch eine Proliferation und Differenzierung von Fibroblasten in Myofibroblasten gekennzeichnet ist, die zu einer Ablagerung von Kollagen im interstitiellen Gewebe führt und so eine respiratorische Insuffizienz induziert. Ziel dieser Forschungsarbeit ist es, die Wirkung eines Extrakts aus Lavandula stoechas (Lavendel) auf die durch Bleomycin induzierte Lungenfibrose (BLM) bei Wistar-Ratten zu bewerten.Unsere phytochemischen Ergebnisse zeigen, dass der Lavendelextrakt eine hohe antioxidative Aktivität besitzt und einen hohen Gehalt an phenolischen Verbindungen aufweist. Die pathologisch-anatomische Untersuchung ergab einen Rückgang des Fibrose-Scores in den mit Lavandula stoechas behandelten Gruppen bei gleichzeitiger Verbesserung der Lungenarchitektur. Unsere Ergebnisse zeigten auch eine Normalisierung der Werte der Marker für oxidativen Stress und der LDH. Zusammenfassend hat diese Arbeit gezeigt, dass unser Lavendel-Extrakt eine interessante antifibrotische und antioxidative Aktivität mit einem therapeutischen Promotor-Effekt gegen Lungenfibrose aufweist.

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