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Investigações farmacológicas sobre o extrato de folhas de Melochia corchorifolia

Investigações farmacológicas sobre o extrato de folhas de Melochia corchorifolia

Palaksha Mekerahally Narayanappa

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Farmacología
ISBN:
9786207632459
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Este trabalho de investigação foi realizado com o objetivo de estabelecer provas científicas sobre a utilização e os conhecimentos folclóricos. O objetivo deste trabalho é a avaliação farmacológica das folhas de Melochia corchorifolia (folclóricas) quanto às actividades antioxidante, diurética, antiurolítica, anticancerígena, antibacteriana e anti-helmíntica. Para o efeito, as folhas de Melochia corchorifolia foram extraídas com clorofórmio e álcool etílico. Os extractos obtidos foram utilizados para actividades farmacológicas, os resultados da atividade antioxidante, os extractos e o seu conteúdo fenólico mostram uma boa atividade de prevenção. A atividade diurética e salurética deve-se à alteração da excreção renal de sódio e a atividade antiurolítica pode dever-se à presença de metabolitos secundários do extrato. Os extractos produziram uma boa atividade anticancerígena nas linhas celulares HCT-116 e MCF-07. Os extractos clorofórmicos de Melochia corchorifolia apresentam boas actividades antibacterianas e anti-helmínticas. Concluiu-se, portanto, que este trabalho de investigação apoia a utilização folclórica deste medicamento à base de plantas (Melochia corchorifolia), que é uma fonte potencial para o tratamento de várias doenças.

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