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Immunohistochemical evaluation of VEGF-C and COX-2 in PTC

Immunohistochemical evaluation of VEGF-C and COX-2 in PTC

Janaina Steger de Oliveira Costa Pires / Vera Saddi

58,82 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Genética (no médica)
ISBN:
9786209211454
58,82 €
IVA incluido
Disponible

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Sobre IBD

Thyroid cancer is the most common malignant neoplasm of the endocrine system. Although it is a relatively rare pathology, accounting for approximately 1% of new cases of malignant diseases, a trend toward increased incidence has been recognized in various parts of the world. This study analyzed the expression of COX-2 and VEGF-C in patients diagnosed with papillary thyroid carcinoma (PTC) in Goiânia, as well as the possible associations between the expression of these markers and the following factors: lymph node metastasis, distant metastasis, tumor size, age, extravasation/invasion of adjacent tissues, and gender. A total of 165 patients with a confirmed histopathological diagnosis of PTC were evaluated. The results of this study corroborate other studies that have demonstrated the usefulness of COX-2 and VEGF-C proteins in identifying PTC patients at higher risk of disease progression due to their association with the presence of regional lymph node metastases and invasion of adjacent tissue.

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