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HYPOPHOSPHATEMIC OSTEOMALACIA

HYPOPHOSPHATEMIC OSTEOMALACIA

Hela Fourati / Zouhour Gassara

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Medicina: cuestiones generales
ISBN:
9786208486297
65,35 €
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Diabetes phosphorus (DP) is a group of rare conditions characterized by renal phosphate leakage, leading to hypophosphatemia and osteomalacia. Although PD-related osteomalacia is much rarer than vitamin D-related osteomalacia, its etiologies are many and varied, including genetic, oncogenic and drug-related causes, as well as tubulopathies. The diagnosis of PD is primarily a biological one, based on hypophosphatemia associated with a low rate of tubular phosphorus reabsorption (TRP). Once the diagnosis has been made, a thorough etiological work-up is required to identify the underlying cause, plan treatment and prevent bone complications. This is based on biology, metabolic imaging and, if necessary, a genetic study. The main objective is to find a curable etiology, in particular an FGF-23-secreting tumour requiring surgical removal. In the absence of an identified cause, PD is said to be idiopathic. Its management is medical, based mainly on optimal phosphorus and calcitriol supplementation.

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Otros libros del autor

  • HYPOPHOSPHATÄMISCHE OSTEOMALAZIEN
    Hela Fourati / Zouhour Gassara
    Phosphatdiabetes (PD) ist eine Gruppe von seltenen Erkrankungen, die durch einen renalen Phosphatverlust gekennzeichnet sind, der zu einer Hypophosphatämie führt, die Osteomalazie verursacht. Obwohl PD-bedingte Osteomalazien viel seltener sind als Vitamin-D-bedingte Osteomalazien, sind ihre Ätiologien vielfältig und umfassen genetische, onkogene und medikamentöse Ursachen sowie...
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  • OSTEOMALÁCIA HIPOFOSFATÉMICA
    Hela Fourati / Zouhour Gassara
    A diabetes fosfórica (DP) é um grupo de doenças raras caracterizadas pela fuga renal de fosfato, levando a hipofosfatemia e osteomalácia. Embora a osteomalácia relacionada com a DP seja muito mais rara do que a osteomalácia relacionada com a vitamina D, as suas etiologias são muitas e variadas, incluindo causas genéticas, oncogénicas e relacionadas com medicamentos, bem como tu...
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  • OSTEOMALACJA HIPOFOSFATEMICZNA
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    Cukrzyca fosforanowa (DP) to grupa rzadkich schorzeń charakteryzujących się nerkowym wyciekiem fosforanów, prowadzącym do hipofosfatemii i osteomalacji. Chociaż osteomalacja związana z PD jest znacznie rzadsza niż osteomalacja związana z witaminą D, jej etiologie są liczne i zróżnicowane, w tym przyczyny genetyczne, onkogenne i związane z lekami, a także tubulopatie. Diagnoza P...
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  • OSTEOMALACIA IPOFOSFATEMICA
    Hela Fourati / Zouhour Gassara
    Il diabete del fosforo (DP) è un gruppo di condizioni rare caratterizzate da perdita di fosfato a livello renale, con conseguente ipofosfatemia e osteomalacia. Sebbene l’osteomalacia correlata al DP sia molto più rara di quella correlata alla vitamina D, le sue eziologie sono numerose e varie, tra cui cause genetiche, oncogeniche e legate ai farmaci, nonché tubulopatie. La diag...
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  • LES OSTEOMALACIES HYPOPHOSPHATEMIQUES
    Hela Fourati / Zouhour Gassara
    Le diabète phosphoré (DP) regroupe un ensemble d’affections rares, caractérisées par une fuite rénale de phosphate, induisant une hypophosphatémie responsable d’ostéomalacie. Bien que les ostéomalacies liées au DP soient beaucoup plus rares que celles liées à la vitamine D, leurs étiologies sont multiples at variées, comprenant les causes génétiques, oncogéniques, médicamenteus...
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