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Group Sequential and Adaptive Methods for Clinical Trials

Group Sequential and Adaptive Methods for Clinical Trials

Bruce W. Turnbull / Christopher Jennison

159,06 €
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Editorial:
Taylor & Francis Ltd
Año de edición:
2025
Materia
Farmacología
ISBN:
9781584888475

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This comprehensive second edition reflects the remarkable evolution in adaptive clinical trial methodology over the past two decades. Since publication of the first edition, these approaches have transformed from theoretical concepts to widely accepted practices, now endorsed by regulatory authorities, including formal FDA guidance.

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Otros libros del autor

  • Group Sequential Methods with Applications to Clinical Trials
    Bruce W. Turnbull / Christopher Jennison
    This book describes group sequential stopping rules designed to reduce average study length and control Type I and Type II error probabilities. The authors present one-sided and two-sided tests, introduce several families of group sequential tests, and explain how to choose the most appropriate test and interim analysis schedule. Their topics include placebo-controlled randomiz...