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Gestione della tossicità epatica e renale indotta dal metotrexato mediante cornus mas

Gestione della tossicità epatica e renale indotta dal metotrexato mediante cornus mas

Hassan Saei Ahan

54,12 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Farmacología
ISBN:
9786208411626
54,12 €
IVA incluido
Disponible

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Il metotrexato, abbreviato MTX e precedentemente noto come ametotropina, è un farmaco antineoplastico, antimetabolita e antifulmine. Viene utilizzato nel trattamento del cancro, delle malattie autoimmuni, della gravidanza ectopica e per l’induzione di aborti medici. Le alterazioni del normale stato redox delle cellule possono causare effetti tossici attraverso la produzione di perossidi e radicali liberi che danneggiano tutti i componenti della cellula, comprese le proteine, i lipidi e il DNA. Gli antiossidanti naturali, come la frutta e la verdura, che forniscono protezione contro i radicali liberi, possono ridurre l’incidenza e i tassi di mortalità del cancro e delle malattie cardiache, oltre agli altri benefici per la salute. I frutti di Cornus mas hanno antociani, flavonoidi e un elevato contenuto di acido ossalico. Contengono anche sostanze antiossidanti, tra cui l’idrossianisolo butirrato e l’idrossitoluene butilato, e hanno il potenziale di combattere il cancro. Il presente studio ha indicato gli effetti epatoprotettivi e nefroprotettivi dell’estratto di frutta di Cornus mas nelle lesioni renali ed epatiche indotte dal metotrexato nel modello di ratto.

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Otros libros del autor

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