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Funkcjonalne działanie flekainidu i amiodaronu

Funkcjonalne działanie flekainidu i amiodaronu

Christian Mayer

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Medicina: cuestiones generales
ISBN:
9786208831196
60,20 €
IVA incluido
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Sobre IBD

Flekainid i amiodaron są ważnymi lekami stosowanymi w leczeniu arytmii, zwłaszcza często występującego migotania przedsionków. Flekainid jest zasadniczo lekiem pierwszego wyboru w tym wskazaniu, ponieważ wykazuje bardzo dobre wskaźniki konwersji i niskie wskaźniki nawrotów w leczeniu długotrwałym. Jest jednak przeciwwskazany u osób z chorobami strukturalnymi serca i znacznie obniżoną czynnością lewej komory, co jednak często ma miejsce w tej grupie pacjentów. W tym przypadku znaczenie ma amiodaron, ponieważ nie ma on negatywnego wpływu na czynność serca. Niemniej jednak bezpośrednie skutki skurczowe i rozkurczowe tych dwóch leków są nadal niedostatecznie poznane, dlatego w niniejszej pracy zbadano je w przedsionkowym mięśniu sercowym człowieka.

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