Estudo

Estudo

Diana Isabella Dmytrow

50,67 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786208565015
50,67 €
IVA incluido
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O objetivo deste estudo é a investigação empírica da frequência da aplicação simultânea de inibidores do CYP3A na rotina clínica. Foi escolhido como método um inquérito retrospetivo e anónimo. A análise produziu os seguintes resultados: 8,57% de dias de internação (27 de 315) e 8,33% de pacientes (4 de 48) foram expostos à aplicação simultânea de inibidores da CYP3A. A frequência da administração simultânea de inibidores do CYP3A é notoriamente elevada em doentes diagnosticados com LMA, uma vez que foi administrado um número acima da média, nomeadamente 0,379 inibidores do CYP3A por dia, em simultâneo. Em comparação, os doentes com NSCLC receberam apenas 0,053 e os doentes com SCLC apenas 0,091 inibidores do CYP3A em simultâneo por dia.A hipótese de que os doentes com LMA têm maior probabilidade de receber inibidores do CYP3A em dias de internamento do que todos os outros doentes foi analisada pelo teste de hipótese qui-quadrado (χ²), coeficiente Phi (ɸ) e índice V de Cramer (CI) e foi considerada significativa.

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  • Study
    Diana Isabella Dmytrow
    The objective of this study is the empirical investigation of the frequency of simultaneously applied CYP3A inhibitors in clinical routine. A retrospective and anonymized survey was chosen as the method. The analysis yielded the following results: 8.57% inpatient days (27 of 315) and 8.33% patients (4 of 48) were exposed to simultaneous application of CYP3A inhibitors. The freq...
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