Espondilite anquilosante

Espondilite anquilosante

Nassima Farah Beldja / Noria Harir

92,37 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
ISBN:
9786209590658
92,37 €
IVA incluido
Disponible

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Sobre IBD

A espondilite anquilosante (EA) é uma doença reumática autoimune crónica que afecta as articulações da coluna vertebral e os tecidos moles adjacentes. Ocorre em pessoas jovens e é predominantemente masculina. Suspeita-se da existência de factores genéticos e ambientais na génese da doença, em particular a vitamina D, o seu recetor (VDR) e o HLAB27.O curso clínico e o prognóstico dependem da idade de início, sendo o início tardio caracterizado por um aumento acentuado dos parâmetros biológicos e doença grave, em comparação com o início precoce.As diferenças de género nas manifestações clínicas podem ser atribuídas a combinações variáveis de determinados haplótipos genéticos. Além disso, os doentes apresentam frequentemente manifestações extra-articulares (EAM), que são elementos importantes para um diagnóstico adequado. Estas incluem a uveíte, a doença inflamatória intestinal crónica (DII), onde está presente em cerca de 2-9% dos casos, e a psoríase.

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