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Efeito do citrato de tamoxifeno nos parâmetros espermáticos e na fragmentação do ADN

Efeito do citrato de tamoxifeno nos parâmetros espermáticos e na fragmentação do ADN

Jabbar Hameed / Muhammad-Baqir Fakhrildin / Noor Kareem Kadhim

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Biologia, ciencias de la vida
ISBN:
9786209261817
59,46 €
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A ativação espermática in vitro é uma etapa muito importante na técnica laboratorial que desempenha um papel importante na determinação do resultado de tecnologias de reprodução assistida, como a inseminação intrauterina (IUI). Além disso, a técnica de preparação espermática utiliza meios de cultura e depende das propriedades dos parâmetros seminais. O citrato de tamoxifeno é um medicamento antiestrogénico com ação antioxidante que inibe a produção de ROS ao interromper a reação em cadeia oxidativa, reduzindo assim o stress oxidativo. Além disso, previne a peroxidação lipídica e aumenta a fluidez e a flexibilidade, o que ajuda o esperma a envolver-se na membrana, eventos de fusão associados à fertilização.

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    Die In-vitro-Spermienaktivierung ist ein sehr wichtiger Schritt in der Labortechnik, der eine wichtige Rolle bei der Bestimmung des Ergebnisses von assistierten Reproduktionstechniken wie IUI spielt. Darüber hinaus wurde bei der Spermienaufbereitungstechnik ein Kulturmedium verwendet, das von den Eigenschaften der Spermienparameter abhängig ist. Tamoxifencitrat ist ein Antiöstr...
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