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Drug Metabolism and Pharmacokinetics Quick Guide

Drug Metabolism and Pharmacokinetics Quick Guide

Cornelis E.C.A. Hop / Harvey Wong / Siamak Cyrus Khojasteh

122,05 €
IVA incluido
Disponible
Editorial:
Springer Nature B.V.
Año de edición:
2011
Materia
Farmacología
ISBN:
9781441956286
122,05 €
IVA incluido
Disponible

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Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. It covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). Overall it includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.

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