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Dose Finding in Drug Development

Dose Finding in Drug Development

Naitee Ting

207,82 €
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Editorial:
Springer Nature B.V.
Año de edición:
2010
Materia
Farmacología
ISBN:
9781441921154
207,82 €
IVA incluido
Disponible

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Sobre IBD

Introduction and New Drug Development Process (Naitee Ting).- Dose Finding Based on Pre-clinical Studies (David Salsburg.- Dose-finding Studies in Phase I and Estimation of Maximally Tolerated Dose (Marlene Modi) .-Dose-finding in Oncology - Non-parametric Methods (Anastasia Ivanova) .- Dose Response in Oncology - Parametric Methods (Mourad Tighiouart and André Rogatko) .- Dose Response - pharmacokinetic-pharmacodynamic approach (Nick Holford) .-General Considerations in Dose Response Study Designs (Naitee Ting) .- Clinical Trial Simulation - a Case Study incorporating efficacy and tolerability dose response (Wayne Ewy, Peter Lockwood, and Candace Bramson) .- Analysis of Dose Response Studies - Emax Model (Jim MacDougall) .- Analysis of Dose Response Studies - Modeling Approaches (José Pinheiro, Frank Bretz, Michael Branson) .- Multiple Comparison Procedures in Dose Response Studies (Ajit Tamhane, Brent Logan) .-Partitioning tests in dose response studies with binary outcome (Xiang Ling, Jason Hsu and Naitee Ting) .- Analysis of Dose Response Relationship Based on Categorical Outcomes (Christy Chuang-Stein, Zhengqing Li) .- Power and Sample Size for Dose Response Studies (Mark Chang, Shein-Chung Chow).

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