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DNA Topoisomerases and Cancer

DNA Topoisomerases and Cancer

Yves Pommier

272,06 €
IVA incluido
Disponible
Editorial:
Springer Nature B.V.
Año de edición:
2013
Materia
Farmacología
ISBN:
9781461429630
272,06 €
IVA incluido
Disponible

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Sobre IBD

DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for the cancer-relevant topoisomerases. It will describe how topoisomerase dysfunctions can damage the genome and increase the risk of cancers, and the involvement of topoisomerases in programmed cell death. The book will also present the various topoisomerase inhibitors in clinical use and development and their molecular and cellular mechanisms of action.

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Otros libros del autor

  • DNA Topoisomerases and Cancer
    Yves Pommier
    DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for the cancer-relevant topoisomerases. It...
    Disponible

    47,06 €

  • DNA Topoisomerases and Cancer
    Yves Pommier
    DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for the cancer-relevant topoisomerases. It...