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Desenvolvimento e caracterização de comprimidos revestidos entéricos de aceclofenaco

Desenvolvimento e caracterização de comprimidos revestidos entéricos de aceclofenaco

Manoj Kumar

66,91 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Farmacología
ISBN:
9786209599040
66,91 €
IVA incluido
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O aceclofenaco é um derivado do ácido fenilacético com propriedades anti-inflamatórias e analgésicas. O aceclofenaco bloqueia diretamente a secreção de PEG-2 no local da inflamação, inibindo a IL e o TNF nas células inflamatórias. O aceclofenaco bloqueia a degeneração e estimula a síntese da matriz extracelular da cartilagem através da inibição das citocinas. Por isso, é utilizado na artrite reumatoide, osteoartrite e espondilite anquilosante. O aceclofenaco tem uma parte ácida que produz úlceras gástricas. Previne úlceras gástricas através do revestimento entérico.

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