Comprimidos Megaloporosos

Comprimidos Megaloporosos

Amrit Lal Patel / Raj K. Keservani / Surya Prakash Gautam

82,91 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786200707093
82,91 €
IVA incluido
Disponible

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A via oral do sistema de administração de fármacos tornou-se cada vez mais importante à medida que os cientistas farmacêuticos adquirem uma melhor compreensão dos aspectos físico-químicos e biológicos relacionados com o seu desempenho. As formulações de matriz e de libertação sustentada acrescentaram novos domínios à administração convencional de medicamentos. O sistema emergente de matriz inerte megaloporosa pode ser visto principalmente como um dispositivo de unidade única que compreende duas fases, que funcionam em conjunto para regular a libertação do fármaco da forma de dosagem com uma taxa constante para os líquidos de dissolução durante um longo período de tempo. Uma das estruturas é denominada grânulo de matriz da fase de restrição (RMG), que inclui o fármaco e o material de controlo da taxa de libertação. A outra estrutura é o grânulo de matriz da fase de alojamento (HMG), que contém o fármaco e um material de controlo da taxa de penetração. Além disso, esta fase desenvolve um sistema de grandes poros interligados.

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