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Citochine

Citochine

Heba Hassan / Mona El-Banna

72,08 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786630357226
72,08 €
IVA incluido
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Le citochine sono piccole proteine regolatrici a basso peso molecolare che coordinano le risposte immunitarie e infiammatorie mediando la comunicazione tra cellule immunitarie e non immunitarie. Vengono classificate come pro-infiammatorie, anti-infiammatorie o pleiotropiche in base alle loro funzioni biologiche. Le citochine agiscono attraverso specifici recettori presenti sulla superficie cellulare, attivando vie di segnalazione quali JAK/STAT, NF-κB, MAPK, PI3K/AKT e SMAD per regolare l’espressione genica, la proliferazione, la differenziazione e la sopravvivenza cellulare. Una segnalazione delle citochine disregolata contribuisce allo sviluppo di malattie autoimmuni, infiammatorie, infettive, metaboliche, cardiovascolari, diabetiche e neurodegenerative. Di conseguenza, le citochine e i loro recettori fungono da importanti biomarcatori e bersagli terapeutici per numerose patologie immuno-mediate.

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