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BIOANALYTICAL ESTIMATION OF IMIQUIMOD IN RABBIT PLASMA BY RP-HPLC

BIOANALYTICAL ESTIMATION OF IMIQUIMOD IN RABBIT PLASMA BY RP-HPLC

Prachet Pinnamaneni

52,26 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2023
Materia
Farmacología
ISBN:
9786206145806
52,26 €
IVA incluido
Disponible

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The present study focuses on the identification and estimation of drugs in the biological matrix using a sophisticated analytical technique also studying their pharmacokinetic parameters like half-lives and rates of elimination and their metabolites in blood. Imiquimod topical treats external warts around the genital and rectal areas called condyloma acuminatum. A direct relationship exists between the drug concentration at the bio-phase (site of action) and the concentration of the drug in plasma. A typical plasma drug concentration-time curve obtained after a single oral dose of a drug and showing various pharmacokinetic and pharmacodynamic parameters.

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