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Avanços nos sistemas lipossómicos de administração de medicamentos

Avanços nos sistemas lipossómicos de administração de medicamentos

Rutuja Chougale

54,38 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Farmacología
ISBN:
9786208077839
54,38 €
IVA incluido
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Este livro apresenta uma análise exaustiva dos sistemas lipossómicos de administração de fármacos, traçando o seu desenvolvimento histórico, vários tipos, mecanismos de encapsulamento e libertação de fármacos, aspectos regulamentares, aplicações clínicas e tendências futuras. Os lipossomas, que são vesículas esféricas com uma bicamada lipídica, transformaram significativamente a administração de fármacos, aumentando a biodisponibilidade, reduzindo a toxicidade e permitindo uma terapia orientada. A evolução da tecnologia lipossómica levou ao desenvolvimento de vários tipos distintos de lipossomas, cada um adaptado a necessidades terapêuticas específicas. Os lipossomas convencionais funcionam como bicamadas lipídicas básicas para o encapsulamento geral de fármacos. Os lipossomas PEGilados, modificados com polietilenoglicol, prolongam o tempo de circulação e melhoram a estabilidade. Os imunolipossomas são conjugados com anticorpos ou ligandos, permitindo a administração dirigida a células específicas.

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