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Astma i zapalenie przyzębia

Astma i zapalenie przyzębia

Deepa Ponnaiyan / Gayathrie Duraisamy

128,48 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Empresa y gestión
ISBN:
9786209385391
128,48 €
IVA incluido
Disponible

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Zapalenie przyzębia jest przewlekłą chorobą zapalną spowodowaną dysbiozą drobnoustrojów, prowadzącą do zniszczenia tkanek i ogólnoustrojowej aktywacji immunologicznej. Pojawiające się dowody wskazują na dwukierunkowy związek między zapaleniem przyzębia a astmą, powiązany przez wspólne szlaki zapalne i mikrobiologiczne. Oba obejmują rozregulowanie cytokin, stres oksydacyjny i aktywację komórek odpornościowych, w szczególności wrodzonych komórek limfoidalnych typu 2 i metaloproteinaz macierzy, które napędzają przebudowę tkanek. Terapie astmy, w tym wziewne kortykosteroidy i beta-2 agoniści, mogą pogarszać stan zdrowia przyzębia poprzez wywoływanie kserostomii i zmian mikrobiologicznych. Czynniki ogólnoustrojowe, takie jak otyłość, GORD i niedobór witaminy D, dodatkowo nasilają stan zapalny w obu zaburzeniach. Zrozumienie ich molekularnego i immunologicznego sprzężenia zwrotnego podkreśla potrzebę zintegrowanego zarządzania w celu kontrolowania ogólnoustrojowego stanu zapalnego i poprawy wyników w zakresie jamy ustnej i układu oddechowego poprzez wspólną opiekę kliniczną i ukierunkowane interwencje.

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