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Analysis of Single-Cell Data

Analysis of Single-Cell Data

Carolin Loos

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Editorial:
Springer Nature B.V.
Año de edición:
2016
Materia
Biologia, ciencias de la vida
ISBN:
9783658132330
67,18 €
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Sobre IBD

Carolin Loos introduces two novel approaches for theanalysis of single-cell data. Both approaches can be used to study cellularheterogeneity and therefore advance a holistic understanding of biologicalprocesses. The first method, ODE constrained mixture modeling, enables theidentification of subpopulation structures and sources of variability in single-cellsnapshot data. The second method estimates parameters of single-cell time-lapsedata using approximate Bayesian computation and is able to exploit the temporalcross-correlation of the data as well as lineage information. 

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