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Análise do citoesqueleto de parasitas patogénicos humanos

Análise do citoesqueleto de parasitas patogénicos humanos

Harald Preisner

100,16 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Empresa y gestión
ISBN:
9786208904012
100,16 €
IVA incluido
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Sobre IBD

O objetivo deste trabalho foi identificar o proteoma completo associado ao citoesqueleto do parasita patogénico humano Trichomonas vaginalis. A atenção centrou-se nas proteínas com arquitetura de sequência repetitiva que estão associadas a estruturas filamentosas e que não podem ser atribuídas à família das proteínas da actina ou da tubulina com base nas suas propriedades. Com base nas descobertas de morfologias citoesqueléticas especializadas de vários protistas, tais como Saccharomyces cerevisae, Tetrahymena thermophila e Giardia lamblia, o objetivo era identificar provas da presença de proteínas de filamentos intermédios (IF) no reino protista e discuti-las no contexto dos organismos metazoários, especialmente porque a presença de proteínas IF fora dos Metazoa era geralmente posta em dúvida pela comunidade de investigação de proteínas IF até ao início deste trabalho.

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