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Tight Junctions

Tight Junctions

Lorenza González-Mariscal

271,35 €
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Editorial:
Springer Nature B.V.
Año de edición:
2010
Materia
Neurología y neurofisiología clínicas
ISBN:
9781441941152
271,35 €
IVA incluido
Disponible

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Sobre IBD

Evolution of the Transporting Epithelium Phenotype.- Occludin, a Constituent of Tight Junctions.- Tight Junction Channels.- JAM Family Proteins.- Cingulin, a Cytoskeleton-Associated Protein of the Tight Junction.- ZO Proteins and Tight Junction Assembly.- TJ Proteins That Make Round Trips to the Nucleus.- Tight Junctions and the Regulation of Epithelial Cell Proliferation and Gene Expression.- Tight Junction Proteins and Cancer.- Regulation of Paracellular Transport across Tight Junctions by the Actin Cytoskeleton.- Regulation of Tight Junctions’ Functional Integrity.- Tight Junctions during Development.- Tight Junctions and the Blood-Brain Barrier.- Tight Junctions in CNS Myelin.- Tight Junction Modulation and Its Relationship to Drug Delivery.

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    This volume explores the dynamic topic of tight junctions. The book focuses on tight junctions’ role in sealing adjacent epithelial cells in a narrow band just beneath their apical surface. The book explains how tight junctions consist of a network of claudins and other proteins, and delves into how they hold cells together and form functional and protective barriers, regulatin...