Dhananjay Mane / JYOTIBA PAWAR
Librería Samer Atenea
Kálamo Books
Librería Elías (Asturias)
Librería Kolima (Madrid)
Librería Proteo (Málaga)
Catalytic reactions encompass a broad range of methodologies, including metal-catalyzed transformations, organocatalysis, and biocatalysis. Transition metal catalysts, such as palladium, copper, and rhodium, have been widely employed in cross-coupling reactions like the Suzuki-Miyaura and Heck reactions, facilitating the construction of complex carbon frameworks found in pharmaceuticals. Organocatalysis, utilizing small organic molecules as catalysts, has emerged as a sustainable alternative, often operating under mild conditions and avoiding the use of heavy metals.The design and synthesis of 4-hydrazinyl-7H-pyrrolo[2,3-d]pyrimidine derivatives and 5-amino-1,3-diphenyl-1H-pyrazole-4-carbonitrile derivatives aim to leverage their heterocyclic scaffolds for potential biological activity, such as antimicrobial, anticancer, or enzyme inhibitory effects. These compounds are structurally tailored to incorporate reactive functional groups-hydrazinyl and amino/nitrile, respectively-that enable further derivatization and enhance interactions with biological targets.
