Staphylococcus epidermidis i biofilm

Staphylococcus epidermidis i biofilm

Anis RADDAOUI

65,49 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
ISBN:
9786209573323
65,49 €
IVA incluido
Disponible

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Niniejszy dokument stanowi dogłębną analizę problemu zakażeń szpitalnych związanych z centralnymi cewnikami żylnymi, powodowanych głównie przez biofilm Staphylococcus epidermidis. Staphylococcus epidermidis jest niezwykle niebezpieczny ze względu na swoją zdolność do tworzenia biofilmu, ustrukturyzowanej społeczności bakterii zamkniętej w ochronnej matrycy. Ten biofilm zapewnia bakteriom wyjątkową tolerancję na antybiotyki i umożliwia im unikanie mechanizmów obronnych układu odpornościowego, co sprawia, że infekcje są bardzo trudne do wyleczenia. Książka szczegółowo opisuje złożone mechanizmy molekularne regulujące tworzenie tego biofilmu, w szczególności kluczową rolę operonu ica i polisacharydu. W obliczu tego poważnego wyzwania klinicznego, tekst zawiera również przegląd różnych strategii walki z nim (impregnowane cewniki, hamowanie komunikacji bakteryjnej, enzymy) i opisuje modele eksperymentalne, zarówno in vitro, jak i in vivo, wykorzystywane do badania tego biofilmu i testowania nowych rozwiązań terapeutycznych.

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