Librería Samer Atenea
Librería Aciertas (Toledo)
Kálamo Books
Librería Perelló (Valencia)
Librería Elías (Asturias)
Donde los libros
Librería Kolima (Madrid)
Librería Proteo (Málaga)
Evolution and Diversity of Prokaryotic Small Heat Shock Proteins.- 1 Introduction.- 2 sHsps in Prokaryotes.- 3 Are sHsps Dispensable in Some Pathogenic Bacteria?.- 4 Phylogenetic Analysis of Prokaryotic sHsps.- 5 Lateral Transfer or Convergent Evolution of Prokaryotic sHsp Genes.- 6 Secondary Structure Prediction of the a-Crystallin Domain.- 7 Alignment and Secondary Structure Prediction of the N-Terminal Domain.- 8 Summary and Concluding Remarks.- References.- Discovery of Two Distinct Small Heat Shock Protein (HSP) Families in the Desert Fish Poeciliopsis.- 1 Introduction.- 2 Variation in Small HSPs Among Desert Species of Poeciliopsis.- 2.1 Results of Survey Among Species.- 2.2 HSP Isoforms as Primary Gene Products.- 2.3 Conclusions.- 3 Variation in Small HSPs Within Poeciliopsis Species.- 3.1 Results of Within-Species Survey.- 3.2 Conclusions.- 4 Discovery of Two Classes of Small HSPs in a Single Taxon.- 4.1 Differential Synthesis.- 4.2 Phosphorylation State of the Small HSPs.- 4.3 Sequence Analysis.- 4.4 Evolutionary Analysis.- 4.5 Conclusions.- References.- Chaperone Function of sHsps.- 1 Introduction.- 2 General Aspect of Chaperone function.- 2.1 Chaperones.- 2.2 Analysis of Chaperone function.- 3 The Chaperone Properties of sHsps.- 3.1 In Vivo Functions of sHsps.- 3.2 sHsps Bind Non-Native Protein.- 3.3 Complex Formation and Substrate Range.- 3.4 The Substrate Binding Site.- 3.5 Mechanism of Substrate Binding.- 3.6 Regulation of Functional Properties.- 3.7 sHsps in the Context of the Cellular Chaperone Machinery.- 4 Conclusions.- References.- The Small Heat Shock Proteins of the Nematode Caenorhabditis elegans: Structure, Regulation and Biology.- 1 Introduction.- 2 The Small Heat Shock Protein Family of C. elegans.- 3 The 16-kDa Stress Proteins (Hspl6s).- 3.1 Hspl6 Gene Organization.- 3.2 Hspl6 Regulation.- 3.3 Biochemical Properties of Hspl6s.- 3.4 Uses of Hspl6 Promoters in C. elegans Research.- 4 The 12-kDa Small Heat Shock Proteins (Hspl2s).- 5 SIP-1.- 6 Hspl7.5.- 7 Hsp25.- 8 Hsp43.- 9 Conclusions and Prospects.- References.- Drosophila Small Heat Shock Proteins: Cell and Organelle-Specific Chaperones?.- 1 Introduction.- 2 Members of the Small Heat Shock Proteins Family.- 3 Transcriptional Regulation.- 3.1 Organisation of Chromatin.- 3.2 Stress-Induced Activation by the Heat Shock Factor.- 3.3 Developmental Transcription of shsp Genes.- 3.3.1 Regulation Cascade Induced by Ecdysone.- 3.3.2 Tissue- and Cell-Specific Enhancers.- 4 Intracellular Localisation-Analysis of Targeting Signals.- 5 Biochemical Properties and Post-Translational Modifications.- 6 Stress-Induced Expression of sHsp.- 6.1 Cell-Specific Response of sHsp.- 6.2 Functions of sHsp Under Stress Conditions.- 7 Developmental Expression of sHsp.- 7.1 Stage, Tissue, and Cell Specificity.- 7.1.1 Embryogenesis.- 7.1.2 Germ Line.- 7.1.3 Ageing.- 7.2 Functions of sHsp During Normal Development.- 7.2.1 Interaction with the SUMO-Conjugating Enzyme Ubc9.- 7.2.2 Modulation of Specific Biological Activity.- 8 Conclusion.- References.- The Developmental Expression of Small HSP.- 1 Introduction.- 2 Small HSP in Extraembryonic Development.- 3 Small HSP in Ectodermal Lineages.- 3.1 Neural Crest Cell Derivatives.- 3.2 Neurectoderm.- 3.3 Expression in the Skin.- 4 Small HSP in Mesodermal Lineages.- 4.1 Small HSP in Muscle Development.- 4.1.1 The Expression Pattern of sHSP in the Heart.- 4.1.2 The Expression Pattern of sHSP in Skeletal and Smooth Muscle.- 4.1.3 The Subcellular Localization of sHSP in Muscle.- 4.2 Small HSP in Other Mesodermal Lineages.- 4.2.1 Expression in Cartilage and Bones.- 4.2.2 Expression in the Derivatives of the Notochord.- 4.2.3 Expression in the Kidney.- 4.2.4 Expression in the Adrenal Glands.- 4.2.5 Expression in the Gonads.- 4.2.6 Expression in the Blood Cells.- 5 Small HSP in Endodermal Lineages.- 5.1 Expression in the Upper Digestive Tract.- 5.2 Expression in the Stomach And Intestine.- 5.3 Expression in the Bladder.- 6 Phosphorylation of ...
