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Sintesi di sulfonammide mediante sulfonamide catalizzata da metallo

Sintesi di sulfonammide mediante sulfonamide catalizzata da metallo

Nagwa Abdelazeem

62,19 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Química
ISBN:
9786207878406
62,19 €
IVA incluido
Disponible

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Sobre IBD

Una sulfonamide è alla base di diversi farmaci sulfamidici. Per questo motivo si è lavorato molto alla creazione di nuove sulfonamidi attraverso la sintesi senza metalli, che utilizza sali solfinati come intermedi o fa reagire composti amminici con cloruri di sulfonile. Purtroppo, i processi utilizzati per sintetizzare i cloruri di sulfonile - come la clorurazione ossidativa dello zolfo dell’organo e la sostituzione elettrofila aromatica con l’acido clorosolfonico - spesso soffrono di condizioni di reazione severe e di un campo di applicazione ristretto. In questo libro vengono quindi discusse numerose tecniche efficaci, come la sintesi catalizzata da metalli di transizione, sviluppate per la sintesi di sulfonammidi.

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