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SARS-CoV-2 Spike Protein Convergent Evolution

SARS-CoV-2 Spike Protein Convergent Evolution

Daniele Focosi

80,46 €
IVA incluido
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Editorial:
Springer Nature B.V.
Año de edición:
2021
Materia
Inmunología
ISBN:
9783030873233
80,46 €
IVA incluido
Disponible

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Sobre IBD

This book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike protein, and profoundly discusses the mechanisms of convergent evolution that led to the rise of these mutated strains at different geographic regions during the Covid-19 pandemic. Furthermore, the book explores how these variants do and may impact the efficacy of established neutralizing antibody-based (nAb) vaccines and therapeutics by analysing latest in vivo and in vitro clinical data. Finally, the author discusses ways on how nAb Covid-19 treatment derived immune escape of SARS-CoV-2 could be minimized in the future.

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