Douglas A. Lauffenburger / Jennifer J. Linderman
Librería Samer Atenea
Librería Aciertas (Toledo)
Kálamo Books
Librería Perelló (Valencia)
Librería Elías (Asturias)
Donde los libros
Librería Kolima (Madrid)
Librería Proteo (Málaga)
Receptors: Models for Binding, Trafficking, andSignaling bridges the gap between chemical engineering andcell biology by lucidly and practically demonstrating how amathematical modeling approach combined with quantitativeexperiments can provide enhanced understanding of cellphenomena involving receptor/ligand interactions. Instressing the need for a quantitative understanding of howreceptor-mediated cell functions depend on receptor andligand properties, the book offers comprehensive treatmentsof both basic and state-of-the-art model frameworks thatspan the entire spectrum of receptor processes--fromfundamental cell surface binding, intracellular trafficking,and signal transduction events to the cell behavioralfunctions they govern, including proliferation, adhesion,and migration. The book emphasizes mechanistic models thatare accessible to experimental testing and includes detailedexamples of important contemporary issues. This much-neededbook introduces chemical engineers and bioengineers to important problems in receptor biology and familiarizes cellbiologists with the insights that can be gained fromengineering analysis and synthesis. As such, chemicalengineers, researchers, and advanced students in the fieldsof biotechnology, biomedical sciences, bioengineering, andmolecular cell biology will find this book to beconceptually rich, timely, and useful.