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Protein-Ligand-, Protein-Inhibitor- und Protein-Protein-Wechselwirkungen

Protein-Ligand-, Protein-Inhibitor- und Protein-Protein-Wechselwirkungen

Sabine Helmsen

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Editorial:
Springer Nature B.V.
Año de edición:
2020
Materia
Química
ISBN:
9783658301507
74,15 €
IVA incluido
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Sobre IBD

Sabine Helmsen stellt die Untersuchung von Interaktionen der Hitzeschockproteine (Hsp) mit Liganden, wie ATP, und potenziellen Inhibitoren in den Fokus ihrer Studie. Diese dienen im Besonderen zur Aufklärung des Bindungsverhaltens mit Hinweisen zu möglichen strukturellen Eigenschaften, welche hinsichtlich der Wechselwirkungen mit Natur- und Wirkstoffen als Inhibitoren eine Rolle spielen. Unter Verwendung der Microarray-Technologie erfolgen schnelle und präzise Analysen, welche ebenfalls den Einfluss bestimmter isolierter Naturstoffe und Extrakte des Pilzes Hypoxylon rickii auf die Wechselwirkung zwischen Hsp70 und Hsp90 zeigen.​Die Autorin:Sabine Helmsen absolvierte den Bachelor of Science in Chemie an der Leibniz Universität in Hannover und schloss den Master Analytik dort am BMWZ, Biomolekulares Wirkstoffzentrum, bei Herrn Professor Kirschning und Herrn PD Zeilinger an.

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